Solutions · Clinical trials

From the inhaler to the digital endpoint.

Respiro turns connected inhalers into objective, trial-grade respiratory data: digital endpoints, eCOA/ePRO-ready measures and audit-ready source data for decentralised and site-based respiratory studies, captured remotely without adding burden to sites or patients.

Digital endpoints & eCOA/ePRO Remote capture & logistics Audit trail & source data Exports, APIs & closeout
Why connected respiratory data

Objective inhaler data, not paper diaries.

Respiratory trials still lean on self-reported diaries and clinic-visit spirometry: sparse, subjective, and easy to miss between visits. A connected inhaler captures what actually happened: every dose, the inhalation behind it and the technique that shaped it, continuously, at home, as objective digital measures your statisticians can work with.

What Respiro brings to a study

Connected devices, mapped to the endpoints you need.

One platform spans the vocabulary trial teams already procure against: from connected-device capture to regulatory-grade endpoints, data exports and real-world follow-on.

Connected devices for trials

RS01X and add-on sensors instrument the study inhaler, capturing dose timing, technique and inhalation profile as device data, without changing how participants inhale.

Digital endpoints

Sensor-derived measures (adherence, inhalation technique, duration, volume and peak inspiratory flow) structured as objective digital endpoints, with documentation to support pre-specified analysis.

eCOA & ePRO-ready

Inhalation and adherence data is built to sit alongside eCOA workflows, pairing objective device measures with patient-reported outcomes in one study record.

Digital biomarkers

Inhalation quality and usage patterns can support exploratory digital biomarkers for respiratory programmes: a window on treatment use and control between visits, not just at them.

Decentralised trials

Data is captured at home and syncs with minimal participant effort, supporting decentralised and hybrid clinical-trial designs while keeping participants in their own routine.

Real-world evidence

The same platform carries from the trial into post-launch real-world evidence: adherence, technique and outcomes at scale, for value-based access and label-supporting studies.

How it fits your protocol

Three steps from device to dataset.

1

Instrument

Add RS01X or an add-on sensor to the study inhaler, define the context of use, and lock the measurement plan before first patient in.

2

Capture

Dose, technique and inhalation data flow in remotely: encrypted, time-stamped, monitored for completeness and handled according to the protocol.

3

Evidence

Structured endpoint datasets, audit records and closeout exports are prepared for your data-management, statistics and regulatory teams.

What sponsors diligence

The clinical-trial checklist, covered.

Pharma teams do not only buy a sensor. They need a defensible data chain for Digital Health Technologies (DHTs): fit-for-purpose measurement, inspection-ready records, integrations that do not trap the data, and operational support that keeps sites and participants moving.

Endpoint specification

Define exactly what the device contributes to the protocol: captured events, units, derivation rules, expected use windows, missing-data handling and statistical handoff.

  • Adherence, dose timing and inhalation-profile digital measures
  • Validation evidence mapped to the study context of use
  • Analysis-ready definitions before data collection starts

Source data and audit trail

Preserve the evidence chain from remote device capture to durable repository, with secure access, time stamps, metadata and audit records configured to the sponsor's study requirements.

  • 21 CFR Part 11 and EU GCP-oriented controls where applicable
  • Role-based access and inspection-ready source records
  • Documented data retention and archiving plan

Exports and integrations

Give data-management teams usable outputs instead of a closed dashboard: study exports, APIs and handoff formats that can feed EDC, eCOA/ePRO, eSource, biostatistics and data warehouses.

  • CSV or structured data exports for analysis workflows
  • APIs and webhooks for configured study integrations
  • CDISC-friendly mapping discussions with the sponsor team

Device operations

Plan the physical study reality: provisioning, labelling, pairing, shipment, replacement, returns and technical support for patients, sites and study teams.

  • Study configuration and user-acceptance testing
  • Site and participant training materials
  • Replacement and support workflows for device issues

Data quality monitoring

Track completeness, sync status, signal plausibility and protocol adherence while the study is running, so issues can be corrected before the database is locked.

  • Connectivity and missing-data visibility
  • Configurable review and escalation workflows
  • Site-ready summaries for study oversight

Security and closeout

Support the end-to-end data lifecycle: encryption, privacy controls, access revocation, final data transfer, archive package and decommissioning steps.

  • GDPR/HIPAA-aligned deployment options
  • Retention and certified-copy expectations planned upfront
  • Closeout procedures for data, devices and accounts

Specific controls, export formats, system validation evidence and regulatory wording are confirmed for each protocol, market and sponsor SOP. Respiro can support study teams during endpoint planning, vendor qualification and data-transfer design.

Measurement you can defend

An independent clinical study found RS01X's on-device readings of inhalation duration, volume and peak inspiratory flow agreed closely with a laboratory reference instrument, so what the device reports stands up as measurement, not estimate.

Validation study, Int. J. COPD (2025). See the full evidence base on our research page.

Built for regulated research

Trial-grade by design, not by retrofit.

Respiro is developed under an ISO 13485:2016 quality system and delivered on secure cloud infrastructure, with GDPR- and HIPAA-aligned deployments and documentation oriented to EU MDR, FDA digital-health-technology guidance, 21 CFR Part 11 expectations and EU computerised-systems guidance where applicable. Endpoint definitions, validation scope, system configuration and regulatory wording are confirmed per study and market.

Bring objective respiratory endpoints to your trial.

Tell us about your programme and the endpoints you're chasing. We'll show how connected inhalers and the Respiro platform fit your protocol, your sites and your regulatory plan.